Introduction

The Functional Neurogenomics research group led by Philipp Abe investigates the molecular foundations of brain development, with a particular focus on the formation of neuronal circuits. Within the framework of the “ThalamoConnect” project, state-of-the-art single-cell technologies and bioinformatic analyses are employed to decipher the genetic programs that govern the connectivity of brain regions and contribute to neurological disorders when disrupted.

Your Role – Where Your Expertise Is Needed:

• Performing neuronal tracing to analyze the development of brain circuits in mouse models
• Applying tissue clearing techniques and light-sheet microscopy for 3D imaging of the entire mouse brain
• Analyzing and interpreting single-cell genomics data to investigate cellular mechanisms
• Functional validation of newly identified neuronal connections and gene functions
• Contributing to the preparation of scientific publications and supporting project and third-party funding applications with the aim of completing a doctorate (Ph.D. / Dr. rer. medic.)
• Supervising and providing technical support to students (Bachelor’s, Master’s, medical students) in daily laboratory and project work
• Participating in the planning and organization of experimental workflows in the laboratory

Your Profile – A Perfect Fit:

• Completed university degree in biology, neuroscience, molecular medicine, biochemistry, or a comparable field
• Experience in handling mouse models and basic surgical techniques
• Knowledge of omics data analysis (e.g., single-cell genomics)
• Experience with advanced imaging and microscopy techniques is desirable
• Strong interest in interdisciplinary research and independent work in an experimental laboratory
• High level of care and precision in the planning, execution, and evaluation of experiments
• Patience and perseverance for complex research projects and long-term analyses
• Team spirit and strong communication skills for close collaboration in interdisciplinary teams

Our Offer –

at the Institute of Clinical Genetics

The doctoral position is available as soon as possible and is initially limited to a period of three years. Remuneration is based on the pay scale regulations of the Collective Agreement for the Public Service of the Federal States (TV-L) and, subject to personal eligibility, is possible at pay group E13 (65% doctoral position).

Convincing Across the Board:

• A stimulating research environment at a leading university medical center
• Access to state-of-the-art multiomics and imaging platforms
• Close supervision and integration into collaborative research networks
• Compensation: In accordance with the collective agreement, plus an annual special payment, subject to personal eligibility
• Leave: 30 days of paid annual leave
• Professional Development: Extensive internal and external training and continuing education opportunities to continuously strengthen your skills
• Work Culture: We value transparency, teamwork, and shared success. Join us at social events or sporting activities such as the REWE Team Challenge
• Mobility: Job bike program and subsidy for public transport tickets to support an environmentally friendly and convenient commute
• Health & Well-being: Access to modern sports and exercise programs at our health center, mental health initiatives, and comprehensive occupational health management
• Employee Benefits: Discounts at our hospital pharmacy, exclusive corporate benefits, and additional shopping platforms
• Work–Life Balance: Our family office supports you with childcare, holiday programs, and care for relatives. We also offer flexible working models